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KMID : 1013220190170010038
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Jouranl of the Korean Society of Clinical Toxicology
2019 Volume.17 No. 1 p.38 ~ p.41
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Elevation of Procalcitonin in an Adolescent Acetaminophen Intoxication
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Kim So-Eun
Lee Jae-Baek
Jin Young-Ho
Yoon Jae-Chol
Jo Si-On
Jeong Tae-Oh
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Abstract
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Procalcitonin (PCT) is commonly employed in medical practice as a diagnostic biomarker of bacterial infection and also as a monitoring biomarker for antimicrobial therapy. There have been a few published reports concerning elevated PCT levels in people with acute liver injury caused by an overdose of acetaminophen. We report here on a case of PCT elevation in an adolescent with acute acetaminophen poisoning without any bacterial infection or liver injury. A 15-year-old girl had deliberately ingested 20 tablets of 650 mg acetaminophen (13 g) and she presented to our emergency department. The PCT level on admission was elevated to 65.64 ng/mL (reference range: 0-0.5 ng/mL). Her PCT level on the second day peaked up to 100 ng/mL and then it gradually decreased. There was no evidence of liver injury or infection on the computed tomography examination and other lab tests. The patient regained her good health and was discharged on the sixth day of hospitalization.
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KEYWORD
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Procalcitonin , Liver injury , Acetaminophen intoxication , Adolescent
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